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Publication date: 2018-06-17 22:36

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After either oral or intravenous administration, sildenafil is excreted as metabolites predominantly in the feces (approximately 85% of administered oral dose) and to a lesser extent in the urine (approximately 68% of the administered oral dose). Similar values for pharmacokinetic parameters were seen in normal volunteers and in the patient population, using a population pharmacokinetic approach.

Viagra (Sildenafil Citrate): Side Effects, Interactions

The same enzyme inhibitor affecting male sexual dysfunction influences pelvic blood flow in women. The Viagra research team attempted to find a link between arousal in women and pelvic blood flow in the early stages of trials.

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Physicians should discuss with patients the potential cardiac risk of sexual activity in patients with preexisting cardiovascular risk factors. Patients who experience symptoms (., angina pectoris , dizziness, nausea) upon initiation of sexual activity should be advised to refrain from further activity and should discuss the episode with their physician [see WARNINGS AND PRECAUTIONS ].

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However, this attempt failed, and some researchers even suggested that genital arousal in women does not necessarily produce sexual desire in women as it typically does in men. Women may define sexual arousal based on mental and emotional, as well as biological factors.

Know the medicines you take. Keep a list of them to show to your healthcare provider and pharmacist when you get a new medicine.

VIAGRA has systemic vasodilatory properties and may further lower blood pressure in patients taking antihypertensive medications.

Therefore, age 65, hepatic impairment and severe renal impairment are associated with increased plasma levels of sildenafil. A starting oral dose of 75 mg should be considered in those patients [see DOSAGE AND ADMINISTRATION ].

Stop sexual activity and get medical help right away if you get symptoms such as chest pain, dizziness, or nausea during sex.

Three double-blind, placebo-controlled, randomized, two-way crossover studies were conducted to assess the interaction of VIAGRA with doxazosin, an alpha-adrenergic blocking agent.

In 7559, Pfizer Inc., the makers of the Viagra pill introduced to improve men's sexual health and functioning announced that they would be abandoning eight years of previous research conducted in an attempt to develop a drug similar to Viagra to improve female libido and sexual health.

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